Recent advances in peroxisome biology

Saturday 29 August from 15:30 to 17:30 - download the programme here (word document)

Eukaryote cells contain various dynamic organelles that continuously adapt their volume fraction and function to prevailing environmental conditions. An organelle that par excellence meets these criteria is the peroxisome. Also, dysfunctioning of peroxisomes is paralleled by severe metabolic disadvantages for the cell/organism in which they occur and is often lethal in man. At present, various aspects of peroxisome biology are still enigmatic and heavily debated. Of these, the principles of peroxisomal matrix protein import, the formation of the peroxisomal membrane (and the role of the ER in this process), the peroxisome fission machinery, solute transport across the peroxisomal membrane and - a very novel field - the role of peroxisomes in ageing and cell death are intensively studied. Recent observations resulted in important novel insights in these processes.

In this sub-group meeting 6 lectures will be presented namely

• 2 lectures on the principles of peroxisomal protein import (J. E. Azevedo, Porto and R. Erdmann, Bochum)
• 2 lectures on the peroxisomal protein fission machinery (E. H. Hettema, Sheffield and M. Schrader, Aveiro)
• 1 lecture on solute transport across the peroxisomal membrane (R. J. Wanders/ H. R. Waterham, Amsterdam)
• 1 lecture on the role of peroxisomes in ageing and cell death (I.J. van der Klei/ M. Veenhuis, Groningen)

Registration Contact:

Ida van der Klei, University of Groningen, The Netherlands

Phone: +31 50 363 2179
Fax: +31 50 363 8280
E-mail: i.j.van.der.klei@rug.nl This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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