Principles of microtubule regulation Saturday 29 August from 14:30 to 17:30
Focus of the sub-group:
Microtubules are involved in a wide range of different cellular functions. They organize the intracellular space, serve as tracks for intracellular transport, build the mitotic apparatus that separates the chromosomes during cell division, and they are the major building blocks of complex structures such as the cilia, flagella and the centrosome. Many if not all of the functions of microtubules are mediated by interactions with specific proteins, commonly referred to as microtubule-associated proteins (MAPs), which range from simple microtubule binders to motile proteins (molecular motors) and proteins that are specifically localized to parts of the microtubule, such as the plus end. The functions of many MAPs have been explored in the past; however, it still is not well understood how different MAPs can selectively bind to subsets of microtubules, or only two a portion of a single microtubule filament. In this subgroup meeting we want to discuss new discoveries on mechanisms that could underlie selective interactions of MAPs with microtubules.
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